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2024, Vol: 11, Issue: 2
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Online Published: 24 Jan 2019
 


EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS

Ukwuani A. N., Ibrahim S. A..


Abstract
Bone-setting as an alternative health service, is an old practice in African societies and is available and accessible to people in both rural and urban centers. In northern Nigeria, preparations of Ficus platyphylla, in combination with other plants, have been used in traditional medicine for the management of fractured bones. This work investigated the analgesic activity of F. platyphylla sequential stem bark fractions in albino rat. The results show that methanol and water fractions significantly (P<0.05) prolonged the pain reaction times in tail flick pain model. Also, all fractions significantly (P< 0.01) reduced acetic acid—induced writhing compared to the control. This was comparable to Aspirin, the standard drug. Phytochemical analysis reveal the presence of saponins, terpenoids, steroids, anthraquinone, glycosides, cardenolides and tannins. These findings suggest that F. platyphylla stem bark possess effective analgesic activity mediated via central and peripheral mechanisms and could be beneficial in alleviating painful inflammatory conditions.

Key words: Ficus platyphylla, analgesic; writhing, stem bark, Bone-setting


 
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Pubmed Style

N. UA, A. IS. EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equijost. 2014; 2(1): 1-5.

Web Style

N. UA, A. IS. EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. https://www.equijost.com/?mno=302643977 [Access: June 29, 2026].

AMA (American Medical Association) Style

N. UA, A. IS. EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equijost. 2014; 2(1): 1-5.


Vancouver/ICMJE Style

N. UA, A. IS. EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equijost. (2014), [cited June 29, 2026]; 2(1): 1-5.


Harvard Style

N., U. A. & A., . I. S. (2014) EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equijost, 2 (1), 1-5.


Turabian Style

N., Ukwuani A., and Ibrahim S. A.. 2014. EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equity Journal of Science and Technology, 2 (1), 1-5.


Chicago Style

N., Ukwuani A., and Ibrahim S. A.. "EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS." Equity Journal of Science and Technology 2 (2014), 1-5.


MLA (The Modern Language Association) Style

N., Ukwuani A., and Ibrahim S. A.. "EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS." Equity Journal of Science and Technology 2.1 (2014), 1-5. Print.


APA (American Psychological Association) Style

N., U. A. & A., . I. S. (2014) EVALUATION OF ANALGESIC EFFECTS OF Ficus platyphylla SEQUENTIAL STEM BARK EXTRACTS IN ALBINO RATS. Equity Journal of Science and Technology, 2 (1), 1-5.




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